Imazethapyr in water and air: safety profile
Low risk(People-specific data is limited; this page draws from human adult context.) Imazethapyr is an imidazolinone (ALS/AHAS-inhibiting) herbicide with very low mammalian toxicity. Oral LD50 rat >5000 mg/kg. EPA Group E (evidence of non-carcinogenicity). NOAEL 500 mg/kg/day — the highest NOAEL tested — no adverse effects observed at any dose in chronic studies. Used widely in soybeans and Clearfield rice/wheat systems.
What is imazethapyr?
Also known as: Pursuit, Newpath, AC 263499, 5-ethyl-2-(4-isopropyl-4-methyl-5-oxo-4,5-dihydro-1H-imidazol-2-yl)nicotinic acid.
- CAS number
- 81335-77-5
- Molecular formula
- C15H19N3O3
- Molecular weight
- 289.33 g/mol
- SMILES
- CCC1=CC(=C(N=C1)C2=NC(C(=O)N2)(C)C(C)C)C(=O)O
- PubChem CID
- 54740
Risk for people
Low riskImazethapyr is an imidazolinone (ALS/AHAS-inhibiting) herbicide with very low mammalian toxicity. Oral LD50 rat >5000 mg/kg. EPA Group E (evidence of non-carcinogenicity). NOAEL 500 mg/kg/day — the highest NOAEL tested — no adverse effects observed at any dose in chronic studies. Used widely in soybeans and Clearfield rice/wheat systems.
Regulatory consensus
2 regulatory and scientific bodies have classified Imazethapyr. The classifications differ — that's the data.
| Agency | Year | Classification | Notes |
|---|---|---|---|
| EPA | 2006 | Group E — Not carcinogenic | |
| EU | 2002 | Not approved (not submitted for EU registration) |
Regulators apply different standards of evidence — animal-data weighting, exposure-pattern assumptions, epidemiological power thresholds — which is why two scientific bodies can review the same data and reach different conclusions. The disagreement is the data.
Where you encounter imazethapyr
- Agriculture
- Water
Frequently asked questions
No FAQ entries generated.
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Reference data, not professional advice. Aggregates publicly available regulatory and scientific data; not a substitute for veterinary, medical, legal, or regulatory advice. Why we built ALETHEIA →