Water & Air / Compounds / Flumioxazin

Flumioxazin in water and air: safety profile

Moderate risk

(People-specific data is limited; this page draws from human adult context.) Flumioxazin is a PPO (protoporphyrinogen oxidase)-inhibiting herbicide used pre-emergence in soybeans, peanuts, and ornamentals. Low mammalian acute toxicity: oral LD50 rat >5000 mg/kg. NOAEL 5 mg/kg/day from developmental toxicity study in rabbits. Classified as a developmental toxicant — teratogenic in rabbits at maternally toxic doses (ventricular septal defects). Not classified as carcinogenic.

What is flumioxazin?

Also known as: Valor, Broadstar, Flumyzin, S-53482.

CAS number
103361-09-7
Molecular formula
C12H9FN2O4
Molecular weight
354.33 g/mol
SMILES
C1C=CC2(C1)C(=O)N(c3cc4c(cc3F)OC(=O)C4=O)C2=O
PubChem CID
92425

Risk for people

Moderate risk

Flumioxazin is a PPO (protoporphyrinogen oxidase)-inhibiting herbicide used pre-emergence in soybeans, peanuts, and ornamentals. Low mammalian acute toxicity: oral LD50 rat >5000 mg/kg. NOAEL 5 mg/kg/day from developmental toxicity study in rabbits. Classified as a developmental toxicant — teratogenic in rabbits at maternally toxic doses (ventricular septal defects). Not classified as carcinogenic.

Regulatory consensus

2 regulatory and scientific bodies have classified Flumioxazin. The classifications differ — that's the data.

AgencyYearClassificationNotes
EPA2001Registered; developmental toxicant flag
EU2003Approved under Regulation (EC) 1107/2009; classified Repr. 2 H361d

Regulators apply different standards of evidence — animal-data weighting, exposure-pattern assumptions, epidemiological power thresholds — which is why two scientific bodies can review the same data and reach different conclusions. The disagreement is the data.

Where you encounter flumioxazin

  • Agriculture
  • Water

Safer alternatives

Lower-risk approaches that achieve a similar outcome to Flumioxazin:

  • Saflufenacil
    Trade-offs: Newer chemistry, fewer use sites registered. Higher cost.
    Relative cost: Higher

Frequently asked questions

No FAQ entries generated.

See Flumioxazin in the water app

Look up products containing flumioxazin, compare to alternatives, and explore the full data record.

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Sources (1)
  1. EPA Registration — Flumioxazin — epa

Reference data, not professional advice. Aggregates publicly available regulatory and scientific data; not a substitute for veterinary, medical, legal, or regulatory advice. Why we built ALETHEIA →