Water & Air / Compounds / DBNPA

DBNPA in water and air: safety profile

Moderate risk

(People-specific data is limited; this page draws from human adult context.) Safety profile for DBNPA relevant to people.

What is dbnpa?

The IUPAC name is 2,2-dibromo-3-nitrilopropionamide.

Also known as: 2,2-dibromo-3-nitrilopropionamide, Tektamer, Napabrom, N-Chloroacetanilide.

IUPAC name
2,2-dibromo-3-nitrilopropionamide
CAS number
10222-01-2
Molecular formula
C3H4Br2N2O
Molecular weight
243.88 g/mol
SMILES
CC(=O)N(C1=CC=CC=C1)Cl
PubChem CID
11365

Risk for people

Moderate risk

Regulatory consensus

2 regulatory and scientific bodies have classified DBNPA. The classifications differ — that's the data.

AgencyYearClassificationNotes
EU_CLPAcute Tox. 2 (Oral); Skin Irrit. 2H300 (Fatal if swallowed), H315 (Causes skin irritation)
EPARegistered as pesticide/biocide; used in industrial water treatment

Regulators apply different standards of evidence — animal-data weighting, exposure-pattern assumptions, epidemiological power thresholds — which is why two scientific bodies can review the same data and reach different conclusions. The disagreement is the data.

Where you encounter dbnpa

  • paper mill systems
  • cooling water
  • industrial disinfection
  • water treatment

Safer alternatives

Lower-risk approaches that achieve a similar outcome to DBNPA:

  • Physical preservation methods (UV treatment, filtration, controlled atmosphere)
    Trade-offs: Removes 95-99% of dissolved contaminants including metals, PFAS, nitrates; wastes 2-4 gallons per gallon produced (improving with newer systems); removes beneficial minerals; $0.05-0.25/gallon; requires pre-treatment for longevity.
    Relative cost: 1.2-2×
  • Naturally-derived antimicrobials (essential oil components at validated concentrations)
    Trade-offs: Removes 95-99% of dissolved contaminants including metals, PFAS, nitrates; wastes 2-4 gallons per gallon produced (improving with newer systems); removes beneficial minerals; $0.05-0.25/gallon; requires pre-treatment for longevity.
    Relative cost: 2-5× conventional
  • Hurdle technology combining multiple mild preservation methods
    Trade-offs: Alternative approach; specific tradeoffs depend on application context, scale, and regulatory requirements. Full hazard assessment of alternative recommended before adoption to avoid regrettable substitution.
    Relative cost: 1.2-2×

Frequently asked questions

What products contain dbnpa?

DBNPA appears in: paper mill systems; cooling water; industrial disinfection.

See DBNPA in the water app

Look up products containing dbnpa, compare to alternatives, and explore the full data record.

Open in water View raw API data

Sources (2)

  1. PubChem Compound CID 11365 — database
  2. ATSDR Toxicological Profile — CAS 10222-01-2 — reference

Reference data, not professional advice. Aggregates publicly available regulatory and scientific data; not a substitute for veterinary, medical, legal, or regulatory advice. Why we built ALETHEIA →